You can add guides in 2 ways:
When you create a guide you can set the distance from the top left of the page, either horizontally or vertically. You can set which page the guide appears on. And if it is a Page Guide or Document Guide.
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You can drag a guide to move it, unless it is locked.
To edit an individual guide right-click on it to bring up the context menu. From here you can:
The Grid and Guide Settings allow you:
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